ATF2 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesHB16; CREB2; TREB7; CRE-BP1; MGC111558; ATF2
ProductOrderA
Clone#4F12
Entrez GenelD1386
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human ATF2 expressed in E. Coli.
MW55kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman, Mouse
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
WB (Western Blot)1/500 - 1/2000
Sequence
263-454
Catalog#: 30164
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Images
Western Blot
Figure 1: Western blot analysis using ATF2 mouse mAb against NIH/3T3 cell lysate.
Figure 1: Western blot analysis using ATF2 mouse mAb against NIH/3T3 cell lysate.
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded lung cancer (left) and brain tissues (right) using ATF2 mouse mAb with DAB staining.
Figure 2: Immunohistochemical analysis of paraffin-embedded lung cancer (left) and brain tissues (right) using ATF2 mouse mAb with DAB staining.
Elisa
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
Product Overview
Description

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined.Tissue specificity: Abundant expression seen in the brain.

References (references)
References (references)1. J Dermatol Sci. 2008 Sep;51(3):210-5.
2. J Biol Chem. 2008 Jun 20;283(25):17605-14.