ATF2 Primary Antibody
Item Information
Catalog #
Size
Price
Description
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined.Tissue specificity: Abundant expression seen in the brain.
Product Overview
Entrez GenelD
1386
Aliases
HB16; CREB2; TREB7; CRE-BP1; MGC111558; ATF2
Clone#
4F12
Host / Isotype
Mouse / IgG1
Species Reactivity
Human, Mouse
Immunogen
Purified recombinant fragment of human ATF2 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1. J Dermatol Sci. 2008 Sep;51(3):210-5.
2. J Biol Chem. 2008 Jun 20;283(25):17605-14.
2. J Biol Chem. 2008 Jun 20;283(25):17605-14.
Product Image
Western Blot
![Figure 1: Western blot analysis using ATF2 mouse mAb against NIH/3T3 cell lysate.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/30164lwb.jpg?v=1666699242)
Figure 1: Western blot analysis using ATF2 mouse mAb against NIH/3T3 cell lysate.
Immunohistochemical analysis
![Figure 2: Immunohistochemical analysis of paraffin-embedded lung cancer (left) and brain tissues (right) using ATF2 mouse mAb with DAB staining.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/30164ihc.jpg?v=1666699242)
Figure 2: Immunohistochemical analysis of paraffin-embedded lung cancer (left) and brain tissues (right) using ATF2 mouse mAb with DAB staining.
Elisa
![Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/30164ea.jpg?v=1666699242)
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
For Research Use Only. Not for use in diagnostic procedures.