Androgen receptor Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesNR3C4; KD; AIS; SMAX1; HUMARA; AR
ProductOrderA
Clone#2H8
Entrez GenelD367
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human AR expressed in E. Coli.
MW110kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
WB (Western Blot)1/500 - 1/2000
Sequence
221-321(Atalas)
Catalog#: 30007
Inquire
Contact us to order
Images
Western Blot
Figure 1: Western blot analysis using Androgen receptor mouse mAb against K562 (1), Jurkat (2) and LNCaP (3) cell lysate.
Figure 1: Western blot analysis using Androgen receptor mouse mAb against K562 (1), Jurkat (2) and LNCaP (3) cell lysate.
Western Blot
Figure 2: Western blot analysis using Androgen receptor mAb against human Androgen receptor (AA: 221-321) recombinant protein. (Expected MW is 40 kDa)
Figure 2: Western blot analysis using Androgen receptor mAb against human Androgen receptor (AA: 221-321) recombinant protein. (Expected MW is 40 kDa)
Western Blot
Figure 3: Western blot analysis using Androgen receptor mouse mAb against Androgen receptor (aa221-321)-hIgGFc transfected HEK293 cell lysate.
Figure 3: Western blot analysis using Androgen receptor mouse mAb against Androgen receptor (aa221-321)-hIgGFc transfected HEK293 cell lysate.
Immunohistochemical analysis
Figure 4: Immunohistochemical analysis of paraffin-embedded human Prostate tissues using Androgen receptor mouse mAb
Figure 4: Immunohistochemical analysis of paraffin-embedded human Prostate tissues using Androgen receptor mouse mAb
Immunohistochemical analysis
Figure 5: Immunohistochemical analysis of paraffin-embedded human human testis (left) and prostate cancer (right) tissues using Androgen Receptor mouse mAb with DAB staining.
Figure 5: Immunohistochemical analysis of paraffin-embedded human human testis (left) and prostate cancer (right) tissues using Androgen Receptor mouse mAb with DAB staining.
Product Overview
Description

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor which is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor. The main function of the androgen receptor is as a DNA binding transcription factor which regulates gene expression; however, the androgen receptor has other functions as well. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype.

References (references)
References (references)1. Chin Med J (Engl). 2009 Nov 20;122(22):2779-83.
2. Taiwan J Obstet Gynecol. 2009 Sep;48(3):262-7.
3. Prostate. 2008 Mar 1;68(4):453-61.
4. Cancer Res. 2007 May 15;67(10):4630-7.