AHR Primary Antibody
Item Information
Catalog #
Size
Price
Description
The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes.
Product Overview
Entrez GenelD
196
Aliases
bHLHe76
Clone#
5E6A9
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human AHR (AA: 721-820) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1.Pharmacol Rev. 2015;67(2):259-79.
2.Int J Cancer. 2015 Jul 15;137(2):299-310.
2.Int J Cancer. 2015 Jul 15;137(2):299-310.
Product Image
Elisa
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using AHR mAb against human AHR (AA: 721-820) recombinant protein. (Expected MW is 37 kDa)
Western Blot
Figure 3:Western blot analysis using AHR mAb against HEK293 (1) and AHR (AA: 721-820)-hIgGFc transfected HEK293 (2) cell lysate.
For Research Use Only. Not for use in diagnostic procedures.