ADAMTS1 Primary Antibody
Item Information
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Size
Price
Description
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.
Product Overview
Entrez GenelD
9510
Aliases
C3-C5; METH1
Clone#
1C12E6
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human ADAMTS1 (AA: 858-960) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Mol Cancer. 2013 Jan 5;12:2.
2.Cancer Sci. 2012 Oct;103(10):1889-97.
2.Cancer Sci. 2012 Oct;103(10):1889-97.
Product Image
Elisa
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using ADAMTS1 mAb against human ADAMTS1 (AA: 858-960) recombinant protein. (Expected MW is 38.3 kDa)
Western Blot
Figure 3:Western blot analysis using ADAMTS1 mAb against HEK293 (1) and ADAMTS1 (AA: 858-960)-hIgGFc transfected HEK293 (2) cell lysate.
Western Blot
Figure 4:Western blot analysis using ADAMTS1 mouse mAb against Hela (1) cell lysate.
Flow cytometric
Figure 5:Flow cytometric analysis of Hela cells using ADAMTS1 mouse mAb (green) and negative control (red).
Flow cytometric
Figure 6:Flow cytometric analysis of K562 cells using ADAMTS1 mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.