AAT Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesPI; A1A; AAT; PI1; A1AT; SERPINA1
ProductOrderA
Clone#2B12
Entrez GenelD5265
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human AAT expressed in E. Coli.
MW47kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman, Mouse
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
aa40-184
Catalog#: 20350
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Images
Western Blot
Figure 1: Western blot analysis using AAT mouse mAb against human plasma (1) and NIH/3T3 cell lysate (2).
Figure 1: Western blot analysis using AAT mouse mAb against human plasma (1) and NIH/3T3 cell lysate (2).
Product Overview
Description

AAT, also known as SERPINA1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1. It is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Severe Serpin A1 deficiency leads to several clinical complications such as pulmonary emphysema, juvenile hepatisis, cirrhosis and hepatocellular carcinoma.

References (references)
References (references)1. J Proteome Res. 2005 Nov-Dec;4(6):2070-80.
2. Neuro Endocrinol Lett. 2008 Aug;29(4):482-4.