VEGFR2 hinge-TM-CD28-CD3z

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Description

VEGFR2 (vascular endothelial growth factor receptor 2) is a type I protein encoded by the KDR gene and expressed on endothelial cells. VEGFs and their receptors are important for angiogenesis and are thus an important therapeutic target for highly vascularized tumors. ProMab's PM-CAR1104 primary human CAR-T cells express an anti-VEGFR2 CAR containing ProMab's VEGFR2-specific scFv, hinge and transmembrane domains, the CD28 costimulatory domain and the CD3zeta activation domain.

Product Overview
Cell Type Tested
T cells
Mycoplasma Testing
The cells has been screened using a PCR-based mycoplasma detection kit to conirm the absence of mycoplasma species.
Storage
-80°C; liquid nitrogen
Shipping & Handing
This product will be shipped in a box containing dry ice at a temperature of -70°C.
For Research Use Only. Not for use in diagnostic procedures.