Mock CAR-T cells (TF-TM-CD28-CD3z)

ProMab’s PM-CAR1061 primary human CAR-T cells express a CAR containing a TF tag, hinge and transmembrane domains, the CD28 costimulatory domain and the CD3zeta activation domain. There is no antigen-binding domain, so these cells can be used as a mock control for ProMab’s antigen-specific CAR-T cells. The cells are generated by transducing activated human T cells with replication-defective lentivirus encoding the mock CAR.

ProMab CAR-T cells are cryopreserved and shipped in vials containing up to 10 million cells. For orders of 100 million cells or more, please inquire. All ProMab cells are guaranteed to be sterile, pathogen-free and mycoplasma-free.