GPC3 CAR-T cells (GPC3 scFv-TM-41BB-CD3z)
Item Information
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Description
GPC3 (glypican-3) is a GPI-linked proteoglycan expressed in hepatocellular carcinoma but not normal liver. GPC3 can also be expressed in other tumors, including melanoma, ovarian clear-cell carcinoma and neuroblastoma.
ProMab's PM-CAR1085 primary human CAR-T cells express an anti-GPC3 CAR containing a GPC3-specific scFv, hinge and transmembrane domains, the 4-1BB costimulatory domain and the CD3zeta activation domain.
Product Overview
Cell Type Tested
T cells
Formulation
CS10 CryoStor Medium (Sigma Aldrich, Cat, #C2874)
Cell Viability
>90%
Mycoplasma Testing
The cells have been screened using a PCR-based mycoplasma detection kit to confirm the absence of mycoplasma species.
Storage
liquid nitrogen
Shipping & Handing
This product will be shipped in a box containing dry ice at a temperature of -70°C.
For Research Use Only. Not for use in diagnostic procedures.