Ustekinumab Biosimilar, Human IL-12/IL-23 mAb
Item Information
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Description
Ustekinumab is a human IgG1-lambda monoclonal antibody specific for human IL-12 and IL-23, two pro-inflammatory cytokines. Ustekinumab represents a novel approach to treating psoriasis, Multiple Sclerosis, Crohn’s Disease and other autoimmune and inflammatory disorders. This Ustekinumab biosimilar has the same amino acid sequence as Ustekinumab.
Product Overview
Isotype
IgG1 lambda
Source
Produced in a mammalian stable cell line.
Formulation
0.2-uM filtered solution, pH 7.4, no stabilizers or preservatives
Purity
>95% by SDS-PAGE under reducing conditions and HPLC
Endotoxin
<1 EU/mg (LAL method)
Specificity/Sensitivity
Binds to human IL-12 and IL-23.
Storage
4°C if used within 1 month, -20°C otherwise
Shipping Information
Shipped with an ice pack.
Application
ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and assays for studying the biological pathways affected by Ustekinumab.
For Research Use Only. Not for use in diagnostic procedures.