Tanezumab Biosimilar, NGF mAb
Item Information
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Description
Tanezumab is a humanized IgG2-kappa monoclonal antibody specific for nerve growth factor (NGF). NGF levels increase during injury and inflammation; Tanezumab relieves the pain associated with these conditions. This Tanezumab biosimilar has the same amino acid sequence as Tanezumab.
Product Overview
Isotype
IgG2 kappa
Source
Produced in a mammalian stable cell line.
Formulation
0.2-uM filtered solution, pH 7.4, no stabilizers or preservatives
Purity
>95% by SDS-PAGE under reducing conditions and HPLC
Endotoxin
<1 EU/mg (LAL method)
Specificity/Sensitivity
Binds to human NGF.
Storage
4°C if used within 1 month, -20°C otherwise
Shipping Information
Shipped with an ice pack.
Application
ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and assays for studying the biological pathways affected by Tanezumab.
For Research Use Only. Not for use in diagnostic procedures.