Pertuzumab Biosimilar, Human HER2 mAb
Item Information
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Description
Pertuzumab is a humanized IgG1-kappa monoclonal antibody specific for human HER2, a protein expressed by a variety of cancers. Pertuzumab is used for the treatment of HER2-positive metastatic breast cancer in combination with trastuzumab and docetaxel.
Product Overview
Isotype
IgG1 kappa
Source
Produced in the CHO stable cell line.
Formulation
0.2-uM filtered solution, pH 6.0, no stabilizers or preservatives
Purity
>95% by SDS-PAGE under reducing conditions and HPLC
Endotoxin
<1 EU/mg (LAL method)
Specificity/Sensitivity
Binds to human HER2.
Storage
4°C if used within 1 month, -20°C otherwise
Shipping Information
Shipped with an ice pack.
Application
ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and assays for studying the biological pathways affected by Pertuzumab.
For Research Use Only. Not for use in diagnostic procedures.