Panitumumab Biosimilar, Human EGFR mAb
Item Information
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Description
Panitumumab is a human IgG2-kappa monoclonal antibody specific for human EGFR. Panitumumab is used for the treatment of refractory EGFR-expressing metastatic colorectal cancer in patients with wild-type KRAS.
Product Overview
Isotype
IgG2 kappa
Source
Produced in the CHO stable cell line.
Formulation
0.2-uM filtered solution, pH 6.0, no stabilizers or preservatives
Purity
>95% by SDS-PAGE under reducing conditions and HPLC
Endotoxin
<1 EU/mg (LAL method)
Specificity/Sensitivity
Binds to human EGFR.
Storage
4°C if used within 1 month, -20°C otherwise
Shipping Information
Shipped with an ice pack.
Application
ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and assays for studying the biological pathways affected by Panitumumab.
For Research Use Only. Not for use in diagnostic procedures.