Infliximab Biosimilar, Human TNF-alpha mAb
Item Information
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Description
Infliximab is a chimeric IgG1 monoclonal antibody specific for TNF-alpha, a pro-inflammatory cytokine produced primarily by M1 macrophages. Infliximab is used to treat autoimmune diseases such as psoriasis, Crohn's disease, ankylosing spondylitis, psoriatic arthritis, rheumatoid arthritis, and ulcerative colitis.
Product Overview
Isotype
IgG1 kappa
Source
Produced in the CHO stable cell line.
Formulation
0.2-uM filtered solution, pH 7.2, no stabilizers or preservatives
Purity
>95% by SDS-PAGE under reducing conditions and HPLC
Endotoxin
<1 EU/mg (LAL method)
Specificity/Sensitivity
Binds to human TNF-alpha.
Storage
4°C if used within 1 month, -20°C otherwise
Shipping Information
Shipped with an ice pack.
Application
ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and assays for studying the biological pathways affected by Infliximab.
For Research Use Only. Not for use in diagnostic procedures.