Animal Supply and Model

Discover the future of scientific research and development with our premier selection of laboratory mice. Our mice are not only carefully bred and meticulously maintained for a wide array of research applications but are also handled with the utmost safety and care, ensuring their well-being throughout the study process. By choosing our mice for your animal study models, you're embracing reliability, reproducibility, and exceptional quality for groundbreaking discoveries, all while adhering to the highest standards of ethical treatment. Partner with us to propel your research projects forward with confidence and unlock new possibilities in the world of science.

Mice Types

BRG Mice

C-NKG-H2-Ab1 KO Mice

NKG

C-NKG B2m KO

Rag1 KO

Rag2 KO

Tcra KO

B6J-Ighm Ighd-DKO

BALB/c-Ighm Ighd-DKO

B6-Ighm KO

BALB/c-Ighm KO

B6-Ighj KO

BALB/c-Ighj KO

Patient Derived Xenograft for In Vivo Pharmacology Studies

Patient-Derived Xenografts (PDX) are advanced cancer models where patient tumor cells are implanted into specially prepared mice, creating a more human-like environment for studying cancer progression, drug efficacy, and resistance. These models offer crucial insights into how therapies will perform in humans, aiding in drug discovery by improving target validation, candidate selection, and identification of patient populations and biomarkers. PDX models stand at the forefront of personalized medicine, enhancing our understanding and treatment of cancer.

Syngeneic Mouse Transplantation Model

Explore Syngeneic Mouse Models for Advanced Oncology Research.

These models, distinct from humanized ones, employ mouse-derived cancer cells for transplantation into genetically similar mice, minimizing rejection risks. Ideal for studying immune response effects on cancer treatments, they highlight differences in drug effectiveness between mice and humans, steering the evolution of cancer research methodologies.

Mouse Skin Transplantation Model

Mouse skin transplantation model offers insights into graft rejection's immunological and pathological mechanisms, emphasizing the T cell's role. Highlighting the procedure's simplicity and the reproducibility of acute skin graft rejection, it outlines the study of allograft rejection.

Mouse Model Bone Marrow Transplantation Model 

Mouse models have been pivotal in the evolution of bone marrow transplantation (BMT) and adoptive T-cell therapy, providing vital insights into the mechanisms of disease and treatment for conditions like multiple myeloma and ataxias. These models have demonstrated the importance of T-cell dynamics in graft-versus-host and graft-versus-leukemia effects, the role of inflammatory cytokines, and the potential of stem cell therapy to restore mobility in movement disorders. Mouse models remain essential for advancing clinical treatments, offering a blend of traditional approaches and cutting-edge techniques to explore new therapeutic pathways.

 

Mouse Kidney Transplantation 

Discover the groundbreaking strides in kidney transplant research. Our work sheds light on the intricate processes of organ rejection, offering a comprehensive tool for understanding both acute and chronic rejection patterns by manipulating donor and recipient genetic backgrounds. With improved surgical techniques for ease and efficiency, this model not only mirrors the challenges faced in human kidney transplants but also paves the way for novel strategies to enhance transplant success and patient outcomes. Learn how our advancements in transplantation science could revolutionize kidney health and recovery.

 

Mouse Model for Islet Transplantation

Discover groundbreaking advancements in islet transplantation research, heralding a new era of hope for individuals with type 1 diabetes. While achieving significant milestones, we acknowledge the journey ahead, marked by challenges such as liver-specific inflammation and intricate immune responses. Join us as we continue to transform promising laboratory breakthroughs into life-changing clinical applications.

Human Immune Checkpoint Gene KI Mouse Model 

Explore the future of oncology drug testing with innovative human immune checkpoint knock-in mouse models. Designed to overcome the limitations of traditional xenografts, our models offer a cost-effective solution for accurately assessing the efficacy and safety of immunomodulatory agents, harnessing the power of a humanized immune system without the need for extensive engraftment. Dive into a new era of precision medicine with our cutting-edge transgenic animal expertise.

 

Cell-Line Derived Xenograft Tumor Models

 

Unlock the potential of cancer treatment with our cutting-edge CDX models. Derived from a diverse range of tumor cell lines, these models excel in adaptability, swiftly forming tumors in immunodeficient mice through various implantation methods. Ideal for preclinical testing, they pave the way for groundbreaking evaluations of drug efficacy, pharmacodynamics, and combination therapies. Despite emerging trends, CDX models stand out for their remarkable consistency and reliability, making them an indispensable tool in the quest for innovative cancer therapies. Dive into the future of cancer research with our CDX models, where precision meets progress.