MSLN Primary Antibody

Item Information
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Description

This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Product Overview
Entrez GenelD
10232
Aliases
MPF; SMRP
Clone#
5C11A4
Host / Isotype
Mouse / IgG1
Immunogen
Mouse IgG1
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Mol Med Rep. 2018 Jan;17(1):1993-1997.
2.Biochemistry. 2017 Jul 5;56(26):3358-3368.
For Research Use Only. Not for use in diagnostic procedures.