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CD49C

Order Information
Catalog# Size/Concentration Price
31492 1.0mg/ml $341.00
Specification
Entrez GeneID 3675
Aliases ITGA3; VL3A; FRP-2; GAPB3; ILNEB; MSK18; VCA-2; VLA3a; GAP-B3
Clone# 5F1D4
MW 116.6kDa
Host/Isotype Mouse IgG1
Storage 4℃; -20℃ for long term storage
Species Reactivity Human;
Immunogen Purified recombinant fragment of human CD49C (AA: extra 63-248) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Application
WB 1/500 - 1/2000
FCM 1/200 - 1/400
ELISA 1/10000
Description
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis.
References
1.Cancer Sci. 2013 Sep;104(9):1189-97.
2.Br J Cancer. 2013 Jun 25;108(12):2516-24.
Sequence
extra(63-248)
Related Products

Western Blot

Figure 1:Western blot analysis using CD49C mAb against human CD49C (AA: extra 63-248) recombinant protein. (Expected MW is 47 kDa)

Elisa

Figure 2:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western Blot

Figure 3:Western blot analysis using CD49C mAb against HEK293 (1) and CD49C (AA: extra 63-248)-hIgGFc transfected HEK293 (2) cell lysate.

Western Blot

Figure 4:Western blot analysis using CD49C mouse mAb against HepG2 (1), HUVEC (2), and HUVE-12 (3) cell lysate.

Flow cytometric

Figure 5:Flow cytometric analysis of HL-60 cells using CD49C mouse mAb (green) and negative control (red).