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CD129

Order Information
Catalog# Size/Concentration Price
31351 1.0mg/ml $341.00
Specification
Entrez GeneID 3581
Aliases IL9R; IL-9R
Clone# 1C2A6
MW 57.1kDa
Host/Isotype Mouse IgG1
Storage 4℃; -20℃ for long term storage
Species Reactivity Human;
Immunogen Purified recombinant fragment of human CD129 (AA: extra 41-270) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Application
WB 1/500 - 1/2000
IHC 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000
Description
The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene.
References
1.Int J Clin Exp Pathol. 2013 Apr 15;6(5):911-6.
2.J Dermatol Sci. 2011 Apr;62(1):16-21.
Sequence
extra(41-270)
Related Products

Elisa

Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western Blot

Figure 2:Western blot analysis using CD129 mAb against human CD129 (AA: extra 41-270) recombinant protein. (Expected MW is 51.9 kDa)

Western Blot

Figure 3:Western blot analysis using CD129 mAb against HEK293 (1) and CD129 (AA: extra 41-270)-hIgGFc transfected HEK293 (2) cell lysate.

Flow cytometric

Figure 4:Flow cytometric analysis of Ramos cells using CD129 mouse mAb (green) and negative control (red).