1.866.339.0871         info@promab.com  info@promab.com

P2RY12

Order Information
Catalog# Size/Concentration Price
31350 1.0mg/ml $341.00
Specification
Entrez GeneID 64805
Aliases HORK3; P2Y12; ADPG-R; BDPLT8; SP1999; P2T(AC); P2Y(AC); P2Y(12)R; P2Y(ADP); P2Y(cyc)
Clone# 1C2A9
MW 39.4kDa
Host/Isotype Mouse IgG1
Storage 4℃; -20℃ for long term storage
Species Reactivity Human;
Immunogen Purified recombinant fragment of human P2RY12 (AA: extra mix) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Application
WB 1/500 - 1/2000
FCM 1/200 - 1/400
ELISA 1/10000
Description
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene.
References
1.BMC Cancer. 2015 Sep 9;15:627.
2.Blood. 2015 Feb 5;125(6):1006-13.
Sequence
extra mix
Related Products

Elisa

Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western Blot

Figure 2:Western blot analysis using P2RY12 mAb against human P2RY12 (AA: extra mix) recombinant protein. (Expected MW is 9.4 kDa)

Western Blot

Figure 3:Western blot analysis using P2RY12 mAb against HEK293 (1) and P2RY12 (AA: extra mix)-hIgGFc transfected HEK293 (2) cell lysate.

Western Blot

Figure 4:Western blot analysis using P2RY12 mouse mAb against PC-3 (1) and C6 (2) cell lysate.

Flow cytometric

Figure 5:Flow cytometric analysis of Hela cells using P2RY12 mouse mAb (green) and negative control (red).