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Order Information
Catalog# Size/Concentration Price
31243 1.0mg/ml $341.00
Entrez GeneID 1173
Aliases mu2; AP50; CLAPM1
Clone# 4F1B2
MW 49.7kDa
Host/Isotype Mouse IgG1
Storage 4℃; -20℃ for long term storage
Species Reactivity Human; Monkey;
Immunogen Purified recombinant fragment of human AP2M1 (AA: 298-435) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
WB 1/300 - 1/800
ELISA 1/10000
This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Three transcript variants encoding different isoforms have been found for this gene.
1.PLoS Pathog. 2012;8(8):e1002845.
2.Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2991-6.
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Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western Blot

Figure 2:Western blot analysis using AP2M1 mAb against human AP2M1 (AA: 298-435) recombinant protein. (Expected MW is 41.8 kDa)

Western Blot

Figure 3:Western blot analysis using AP2M1 mAb against HEK293 (1) and AP2M1 (AA: 298-435)-hIgGFc transfected HEK293 (2) cell lysate.

Western Blot

Figure 4:Western blot analysis using AP2M1 mouse mAb against COS7 (1), SK-Br-3 (2), MCF-7 (3), T47D (4), and HEK293 (5) cell lysate.