Mouse Monoclonal Antibody to JAK2
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| Catalog# |
30041
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| Clone# |
1C1
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| Host and isotype |
Mouse IgG1
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| Species reactivity |
Human
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Lot# |
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| Size |
0.1ml
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Price |
$
280
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| MW |
130.6kDa
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Entrez Gene |
3717
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| Aliases |
JTK10; JAK2
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| Description |
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This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
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| Immunogen |
Purified recombinant fragment of JAK2(745-955aa) expressed in E. Coli.
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| Applications |
Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
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| Formulation |
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Ascitic fluid containing 0.03% sodium azide.
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| Storage |
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Store at 4¡æ, for long term storage, store at -20¡æ.
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| Related product |
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| References |
1. Mol Cell Endocrinol. 1997 May 16;129(2):199-208.
2. J Immunol. 1999 Dec 15;163(12):6651-8.
3. J Biol Chem. 1999 Oct 29;274(44):31531-42.
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Western Blotting
Figure 1: Western blot analysis using JAK2 mouse mAb against THP-1(1) cell lysate.
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| FOR RESEARCH USE ONLY |