Products

Mouse Monoclonal Antibody to JAK2             
 Catalog#   30041   
 Clone#   1C1
 Host and isotype   Mouse IgG1
 Species reactivity   Human  Lot#  
 Size   0.1ml  Price  $ 280
 MW   130.6kDa  Entrez Gene   3717
 Aliases   JTK10; JAK2
 Description
This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
 Immunogen
Purified recombinant fragment of JAK2(745-955aa) expressed in E. Coli.
 Applications
Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
 Formulation
Ascitic fluid containing 0.03% sodium azide.
 Storage
Store at 4¡æ, for long term storage, store at -20¡æ.
 Related product
 References
1. Mol Cell Endocrinol. 1997 May 16;129(2):199-208.
2. J Immunol. 1999 Dec 15;163(12):6651-8.
3. J Biol Chem. 1999 Oct 29;274(44):31531-42.

Western Blotting
Figure 1: Western blot analysis using JAK2 mouse mAb against THP-1(1) cell lysate.

FOR RESEARCH USE ONLY
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