Mouse Monoclonal Antibody to AAT
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| Catalog# |
20350 Mab-2009087
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| Clone# |
2B12
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| Host and isotype |
Mouse IgG1
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| Species reactivity |
Human; Mouse
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Lot# |
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| Size |
0.1ml
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Price |
$
280
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| MW |
47kDa
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Entrez Gene |
5265
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| Aliases |
PI; A1A; AAT; PI1; A1AT; SERPINA1
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| Description |
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AAT, also known as SERPINA1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1. It is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Severe Serpin A1 deficiency leads to several clinical complications such as pulmonary emphysema, juvenile hepatisis, cirrhosis and hepatocellular carcinoma.
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| Immunogen |
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Purified recombinant fragment of human AAT expressed in E. Coli.
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| Applications |
Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
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| Formulation |
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Ascitic fluid containing 0.03% sodium azide.
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| Storage |
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Store at 4¡æ, for long term storage, store at -20¡æ.
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| Related product |
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| References |
1. J Proteome Res. 2005 Nov-Dec;4(6):2070-80.
2. Neuro Endocrinol Lett. 2008 Aug;29(4):482-4.
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Western Blotting
Figure 1: Western blot analysis using anti-AAT mAb against human plasma (1) and NIH/3T3 cell lysate (2).
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| FOR RESEARCH USE ONLY |
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