Mouse Monoclonal Antibody to MYL2
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| Catalog# |
20324 Mab-20090410
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| Clone# |
7C9
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| Host and isotype |
Mouse IgG1
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| Species reactivity |
Human
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Lot# |
|
| Size |
0.1ml
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Price |
$
240
|
| MW |
19kDa
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Entrez Gene |
4633
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| Aliases |
MLC2; CMH10; DKFZp779C0562
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| Description |
|
MYL2(myosin, light chain 2, regulatory, cardiac, slow), also known as MLC-2, MLC2v. Entrez protein NP_000423. MYL2 associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. It is an hexamer of two heavy chains and four light chains that is predominantly expressed in adult cardiac ventricle muscle. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.
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| Immunogen |
Purified recombinant fragment of MYL2 expressed in E. Coli.
|
| Applications |
Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
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| Formulation |
Ascitic fluid containing 0.03% sodium azide.
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| Storage |
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Store at 4¡æ, for long term storage, store at -20¡æ.
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| Related product |
1. #20342, Mouse Monoclonal Antibody to MYL3;
2. #20343, Mouse Monoclonal Antibody to MYL3.
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| References |
1. DNA Seq. 2003 Oct;14(5):339-50.
2. Oncogene. 2002 Aug 29;21(38):5852-60.
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Western Blotting
Figure 1: Western blot analysis using anti-MYL3 (1) and anti-MYL2 (2) monoclonal antibody against rat fetal heart tissue lysate.
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| FOR RESEARCH USE ONLY |
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